It all depends on if you want a distorted sound or a clean one. start by answering that then experiment with different effects or find a guitarists tone you want to sound like. Even if you have the exact same equipment and set up as a guitarist you want to sound like you may not sound like them. The reason is because the style of playing could Also effect your tone. So my best recommendation is listen to other guitars find a style you like and from there create your own based off one you like or combinations of tones and styikes you like.